Article
Hepatic Transporter Expression in Metabolic Syndrome: Phenotype, Serum Metabolic Hormones, and Transcription Factor Expression.
Drug metabolism and disposition: the biological fate of chemicals - 1 Apr 2016
Donepudi Ajay C, Cheng Qiuqiong, Lu Zhenqiang James, Cherrington Nathan J, Slitt Angela L
Abstract excerpt
Metabolic syndrome is a multifactorial disease associated with obesity, insulin resistance, diabetes, and the alteration of multiple metabolic hormones. Obesity rates have been rising worldwide, which increases our need to understand how this population will respond to drugs and exposure to other chemicals. The purpose of this study was to determine in lean and obese mice the ontogeny of clinical biomarkers such...
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