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Article

Switch from Stress Response to Homeobox Transcription Factors in Adipose Tissue After Profound Fat Loss

9 Jun 2010

Abstract excerpt

BACKGROUND: In obesity, impaired adipose tissue function may promote secondary disease through ectopic lipid accumulation and excess release of adipokines, resulting in systemic low-grade inflammation, insulin resistance and organ dysfunction. However, several of the genes regulating adipose tissue function in obesity are yet to be identified. METHODOLOGY/PRINCIPAL FINDINGS: In order to identify novel candidate...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 20543949
DOI: 10.1371/journal.pone.0011033

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