Article
Comparative physiogenomic analyses of weight loss in response to 2 modes of bariatric surgery: demonstration with candidate neuropsychiatric and cardiometabolic genes.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery - 1 Feb 2016
Seip Richard L, Papasavas Pavlos, Stone Andrea, Thompson Stephen, Ng Janet, Tishler Darren S, Ruaño Gualberto
Abstract excerpt
BACKGROUND: Surgical weight loss response is variable, with suboptimal outcomes in some patients. We hypothesized that genetic biomarkers may be related to weight change. METHODS: We tested 330 single nucleotide polymorphisms (SNPs) in genes relevant to metabolic regulation in 161 patients whose decrease in body mass index (BMI), 1 year after laparoscopic adjustable gastric banding (LAGB) or Roux-en-Y gastric...
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