Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.

BMC medical genetics - 5 Mar 2009

Carr Edward J, Clatworthy Menna R, Lowe Christopher E, Todd John A, Wong Andrew, Vyse Timothy J, Kamesh Lavanya, Watts Richard A, Lyons Paul A, Smith Kenneth G C

Abstract excerpt

BACKGROUND: Autoimmune diseases are complex and have genetic and environmental susceptibility factors. The objective was to test the genetic association of systemic lupus erythematosus (SLE) and anti-neutrophil cytoplasmic antibody (ANCA) - associated systemic vasculitis (AAV) with SNPs in the IL2RA region and to correlate genotype with serum levels of IL-2RA. METHODS: Using a cohort of over 700 AAV patients, two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Antibodies, Antineutrophil Cytoplasmic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Enzyme-Linked Immunosorbent Assay

Share to Interleukin-2 Receptor alpha Subunit

Share to Lupus Erythematosus, Systemic

Share to Vasculitis

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 19265545
DOI: 10.1186/1471-2350-10-22
PMCID: PMC2662820

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.PMID 19265545Read ↗

Genetic variants in ANCA-associated vasculitis: a meta-analysis.Semantic proximity Read ↗

Association of IL10RA, IL10RB, and IL22RA Polymorphisms/Haplotypes with Susceptibility to and Clinical Manifestations of SLE.Semantic proximity Read ↗

The genetics of anti-neutrophil cytoplasmic antibody associated vasculitis (AAV)Semantic proximity Read ↗

Evaluating Single-Nucleotide Polymorphisms in Inflammasome Proteins and Serum Levels of IL-18 and IL-1β in Kidney Interstitial Damage in Anti-Neutrophilic Cytoplasmic Antibody-Associated Vasculitis.Semantic proximity Read ↗

Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis.Semantic proximity Read ↗

Genetics of ANCA-associated vasculitides: HLA and beyond.Semantic proximity Read ↗

Gene variants and treatment outcomes in antineutrophil cytoplasmic antibody-associated vasculitis.Semantic proximity Read ↗

Meta-analysis revealed HLA susceptibility markers in ANCA-associated vasculitis and its clinical subtypes.Semantic proximity Read ↗

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.Semantic proximity Read ↗

Polymorphisms of the SERPINA1 gene are associated with higher mortality in a Brazilian cohort of ANCA-associated vasculitis patients.Semantic proximity Read ↗

Interleukin–1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosusSemantic proximity Read ↗

The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.