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Article

ER re-expression and re-sensitization to endocrine therapies in ER-negative breast cancers.

Journal of mammary gland biology and neoplasia - 1 Mar 2009

Brinkman Joeli A, El-Ashry Dorraya

Abstract excerpt

Breast cancer is the leading cause of cancer amongst women in the westernized world. The presence or absence of ERalpha in breast cancers is an important prognostic indicator. About 30-40% of breast cancers lack detectable ERalpha protein. ERalpha- breast cancers are resistant to endocrine therapies and have a worse prognosis than ERalpha+ breast cancers. Since expression of ERalpha is necessary for response to...

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Share to Breast Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Estrogen

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Identifiers

PMID: 19263197
DOI: 10.1007/s10911-009-9113-0

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