Molecular analysis of HLA class I (HLA-A and -B) and HLA class II (HLA-DRB1) genes in Japanese patients with multiple sclerosis (Western type and Asian type).

doi:10.1111/j.1399-0039.1998.tb03084.x

Article

Molecular analysis of HLA class I (HLA-A and -B) and HLA class II (HLA-DRB1) genes in Japanese patients with multiple sclerosis (Western type and Asian type).

Tissue antigens - 1 Dec 1998

Ono T, Zambenedetti M R, Yamasaki K, Kawano Y, Kamikawaji N, Ito H, Sakurai M, Nishimura Y, Kira J, Kanazawa I, Sasazuki T

Abstract excerpt

The types of HLA-A, -B and -DRB1 genes were studied in 146 Japanese patients with multiple sclerosis (MS) using polymerase chain reaction-sequence-specific oligonucleotide probe analysis. Fifty-seven patients who displayed selective clinical involvement of the optic nerve and spinal cord were cla...

Topics

Alleles
HLA-A Antigens
HLA-B Antigens
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Japan
Multiple Sclerosis

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