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Article

Polymorphisms in interleukin-1 receptor-associated kinase 4 are associated with total serum IgE.

Allergy - 1 May 2009

Tewfik M A, Bossé Y, Lemire M, Hudson T J, Vallée-Smejda S, Al-Shemari H, Laprise C, Desrosiers M

Abstract excerpt

BACKGROUND: Serum immunoglobulin E (IgE) level is recognized to be under strong genetic control, but the causal and susceptibility genes remain to be identified. We sought to investigate the association between single nucleotide polymorphisms (SNPs) in the Toll-like receptor (TLR) signaling pathw...

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Source

Identifiers

PMID: 19254290
DOI: 10.1111/j.1398-9995.2008.01889.x

Genes

IRAK4
TLR1
TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19254290-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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