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Article

Association pattern of interleukin-1 receptor-associated kinase-4 gene polymorphisms with allergic rhinitis in a Han Chinese population.

PloS one - 1 Jan 2011

Zhang Yuan, Lin Xiaoping, Desrosiers Martin, Zhang Wei, Meng Na, Zhao Liping, Han Demin, Zhang Luo

Abstract excerpt

OBJECTIVE: Interleukin-1 receptor-associated kinase-4 (IRAK-4) encodes a kinase that is essential for NF-kB activation in Toll-like receptor and T-cell receptor signaling pathways, indicating a possible crosstalk between innate and acquired immunities. We attempted to determine whether the polymorphisms in the Interleukin-1 receptor-associated kinase-4 (IRAK-4) gene are associated with allergic rhinitis (AR) in...

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Identifiers

PMID: 21738793
DOI: 10.1371/journal.pone.0021769
PMCID: PMC3128076

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Source receipt: pubmed, retrieved 7 Sept 2026.

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