Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Early structural changes in individuals at risk of familial Alzheimer's disease: a volumetry and magnetization transfer MR imaging study.

Journal of neurology - 1 Jun 2009

Ginestroni A, Battaglini M, Della Nave R, Moretti M, Tessa C, Giannelli M, Caffarra P, Nacmias B, Bessi V, Sorbi S, Bracco L, De Stefano N, Mascalchi M

Abstract excerpt

Presenilin 1 (PS1) mutation carriers provide the opportunity to asses early features of neurodegeneration in familial Alzheimer's disease (AD). Gray matter (GM) regional volume loss and decrease of magnetization transfer ratio (MTR) consistent with microstructural changes have been reported in sp...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Family
Share to Magnetic Resonance Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuropsychological Tests

Share to Organ Size

Share to Parietal Lobe

Share to Presenilin-1

Share to Temporal Lobe

Source

Identifiers

PMID: 19252791
DOI: 10.1007/s00415-009-5044-3

Genes

MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19252791-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Early structural changes in individuals at risk of familial Alzheimer's disease: a volumetry and magnetization transfer MR imaging study.PMID 19252791Read ↗

Evolving brain structural changes in PSEN1 mutation carriers.Semantic proximity Read ↗

Increased cortical thickness and caudate volume precede atrophy in PSEN1 mutation carriers.Semantic proximity Read ↗

Structural Brain Changes in Pre-Clinical FTD MAPT Mutation Carriers.Semantic proximity Read ↗

Selective brain gray matter atrophy associated with APOE ε4 and MAPT H1 in subjects with mild cognitive impairment.Semantic proximity Read ↗

Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer's disease mutations.Semantic proximity Read ↗

Cortical atrophy in presymptomatic Alzheimer's disease presenilin 1 mutation carriers.Semantic proximity Read ↗

Brain volumetric deficits in MAPT mutation carriers: a multisite study.Semantic proximity Read ↗

Genetic influences on atrophy patterns in familial Alzheimer's disease: a comparison of APP and PSEN1 mutations.Semantic proximity Read ↗

Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease.Semantic proximity Read ↗

H1 haplotype of the MAPT gene is associated with lower regional gray matter volume in healthy carriers.Semantic proximity Read ↗

Enhanced brain activity may precede the diagnosis of Alzheimer's disease by 30 years.Semantic proximity Read ↗

An in vivo study on brain microstructure in biological and chronological ageing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.