Article
The C609T variant of NQO1 is associated with carotid artery plaques in patients with type 2 diabetes.
Molecular genetics and metabolism - 1 May 2009
Han Seung Jin, Kang Eun Seok, Kim Hyeong Jin, Kim So Hun, Chun Sung Wan, Ahn Chul Woo, Cha Bong Soo, Nam Moonsuk, Lee Hyun Chul
Abstract excerpt
OBJECTIVE: Atherosclerosis in patients with type 2 diabetes has been linked to oxidative stress. NADP[1]:quinone oxidoreductase 1 (NQO1) plays a key role in cellular antioxidant defense. Recent reports suggest that highly expressed and inducible endogenous NQO1 from cardiovascular cells may act a...
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