Article
NQO1 C609T Polymorphism is Associated with Coronary Artery Disease in a Gender-Dependent Manner.
Cardiovascular toxicology - 1 Jan 2017
Boroumand Mohammadali, Pourgholi Leyla, Goodarzynejad Hamidreza, Ziaee Shayan, Hajhosseini-Talasaz Azita, Sotoudeh-Anvari Maryam, Mandegary Ali
Abstract excerpt
Findings on the association of NQO1 C609T polymorphism in the NQO1 gene and cardiovascular disease susceptibility are controversial. The objective of the current study was to examine the relationship between this polymorphism and the presence and severity of angiographically determined coronary artery disease (CAD). One-hundred and forty-five patients with newly diagnosed angiographically documented CAD (≥50 %...
Topics
- Aged
- Case-Control Studies
- Chi-Square Distribution
- Coronary Angiography
- Coronary Artery Disease
- Coronary Stenosis
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Heterozygote
- Homozygote
- Humans