Article
Genetic association of Glutathione peroxidase-1 (GPx-1) and NAD(P)H:Quinone Oxidoreductase 1(NQO1) variants and their association of CAD in patients with type-2 diabetes.
Molecular and cellular biochemistry - 1 Feb 2012
Ramprasath Tharmarajan, Murugan Ponniah Senthil, Kalaiarasan Ellappan, Gomathi Pannerselvam, Rathinavel Andiappan, Selvam Govindan Sadasivam
Abstract excerpt
Coronary artery disease (CAD) is a major health concern and the leading cause of death in individuals with type-2 diabetes mellitus (T2DM). Glutathione peroxidase-1 (GPx-1) and NAD(P)H: quinone oxidoreductase (NQO1) are known for its broad range of detoxification. The role of functional variants of these genes in the development of various disorders is proven. Hereby, we investigated the possible role of these...
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