Article
Association of the endothelial nitric oxide synthase (ecNOS) gene polymorphism with carotid atherosclerosis in type 2 diabetes.
Diabetes research and clinical practice - 1 Jun 2006
Park Ji Hyun, Kim Ji Hye, Kim Won Ho, Kim Dal Sik, Park Tae Sun, Baek Hong Sun
Abstract excerpt
This study was done to see whether 27-base pair repeats polymorphism in intron 4 of ecNOS gene is associated with carotid atherosclerosis in type 2 diabetic patients. The polymorphism was identified by polymerase chain reaction (PCR). Ultrasound parameters of carotid atherosclerosis were analyzed in relation to the genotype in 210 patients with type 2 diabetes. The ecNOS4a allele was detected in 34 (16.2%) of...
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