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Article

Polymorphism rs5498 of the ICAM-1 gene affects the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus.

Lipids in health and disease - 18 Apr 2016

Popović Dražen, Starčević Jovana Nikolajević, Letonja Marija Šantl, Makuc Jana, Vujkovac Andreja Cokan, Pleskovič Ruda Zorc, Gaspar Ludovit, Kruzliak Peter, Petrovič Danijel

Abstract excerpt

BACKGROUND: Adhesion molecules are involved in the development of atherosclerosis. An increased level of the ICAM 1 molecule is associated with numerous inflammatory diseases including atherosclerosis of carotid arteries. The rs5498 (K469E) polymorphism of the ICAM-1 gene leads to an increase in the level of serum ICAM. We investigated the association between the rs5498 (K469E) polymorphism of the ICAM-1 gene and...

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Identifiers

PMID: 27090396
DOI: 10.1186/s12944-016-0247-y
PMCID: PMC4835849

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Polymorphism rs5498 of the ICAM-1 gene affects the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus.PMID 27090396Read ↗

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