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Article

Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults.

Experimental gerontology - 1 May 2009

Walston Jeremy D, Matteini Amy M, Nievergelt Caroline, Lange Leslie A, Fallin Dani M, Barzilai Nir, Ziv Elad, Pawlikowska Ludmila, Kwok Pui, Cummings Steve R, Kooperberg Charles, LaCroix Andrea, Tracy Russell P, Atzmon Gil, Lange Ethan M, Reiner Alex P

Abstract excerpt

Interleukin-6 (IL-6) is an inflammatory cytokine that influences the development of inflammatory and aging-related disorders and ultimately longevity. In order to study the influence of variants in genes that regulate inflammatory response on IL-6 levels and longevity, we screened a panel of 477...

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Identifiers

PMID: 19249341
DOI: 10.1016/j.exger.2009.02.004
PMCID: PMC2791897

Genes

PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19249341-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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