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Article

Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: the cardiovascular health study.

Atherosclerosis - 1 Jul 2005

Reiner Alexander P, Diehr Paula, Browner Warren S, Humphries Stephen E, Jenny Nancy S, Cushman Mary, Tracy Russell P, Walston Jeremy, Lumley Thomas, Newman Anne B, Kuller Lewis H, Psaty Bruce M

Abstract excerpt

Inflammatory response genes may influence life span or quality at advanced ages. Using data from the population-based cardiovascular health study (CHS) cohort, we examined the associations between promoter polymorphisms of several inflammation and thrombosis genes with longevity. We ascertained genotypes for interleukin (IL)-6 -174 G/C, beta-fibrinogen -455 G/A, plasminogen activator inhibitor (PAI)-1 -675 4G/5G,...

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Identifiers

PMID: 15939070
DOI: 10.1016/j.atherosclerosis.2005.01.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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