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Article

IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study.

Human genetics - 1 Dec 2007

Walston Jeremy D, Fallin M Daniele, Cushman Mary, Lange Leslie, Psaty Bruce, Jenny Nancy, Browner Warren, Tracy Russell, Durda Peter, Reiner Alex

Abstract excerpt

Interleukin-6 (IL-6) and C-reactive protein (CRP) levels increase with age and likely play a role in adverse health outcomes in older adults. The relationship between IL-6 gene tag single nucleotide polymorphisms (SNPs) and circulating IL-6 and CRP levels, cardiovascular disease (CVD) outcomes, and mortality in Caucasian (CA) and African American (AA) participants of the Cardiovascular Health Study (CHS) was...

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PMID: 17851695
DOI: 10.1007/s00439-007-0428-x

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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