Article
MDM2 309 polymorphism is associated with missed abortion.
Human reproduction (Oxford, England) - 1 Jun 2009
Fang Yan, Kong Beihua, Yang Qifeng, Ma Daoxin, Qu Xun
Abstract excerpt
BACKGROUND: In this study, we assessed whether the single nucleotide polymorphism in the murine double minute 2 (MDM2) promoter (SNP309) was associated with the occurrence of missed abortion. METHODS: Genotyping of MDM2 SNP309 polymorphism was conducted by polymerase chain reaction-restriction fragment length polymorphism with blood and villous samples from 95 women diagnosed as having 1st trimester missed...
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