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Article

Polymorphism of MDM2 promoter 309 (rs 2279744) and the risk of PCOS.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jan 2016

Chan Ying, Jiang Hongguo, Yang Xiaoling, Li Dongya, Ma Lan, Luo Ying, Tang Wenru

Abstract excerpt

This study aimed at evaluating possible association between MDM2 SNP309 polymorphism (rs 2279744) and polycystic ovary syndrome (PCOS). One hundred and twenty-five women with PCOS and two hundred and fifty women without PCOS were collected from the department of reproductive medicine of college hospital in this case-control study. Peripheral blood samples were collected from all participants and DNA was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26440054
DOI: 10.3109/09513590.2015.1092515

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphism of MDM2 promoter 309 (rs 2279744) and the risk of PCOS.PMID 26440054Read ↗

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MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studies.Semantic proximity Read ↗

Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer.Semantic proximity Read ↗

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