Article
The MDM2 promoter T309G polymorphism was associated with preeclampsia susceptibility.
Journal of assisted reproduction and genetics - 1 Jul 2017
Salimi Saeedeh, Mohammadpour-Gharehbagh Abbas, Rezaei Mahnaz, Sajadian Mojtaba, Teimoori Batool, Yazdi Atefeh, Mokhtari Mojgan, Yaghmaei Minoo
Abstract excerpt
PURPOSE: Preeclampsia (PE) is a hypertensive disorder of pregnancy in which abnormal proliferation and apoptosis of placenta trophoblast has a pivotal role in its pathophysiology. The aim of the current study was to examine the association between Mouse Double Minute 2 (MDM2) T309G and 40 bp insertion/deletion (I/D) polymorphisms and PE risk. METHODS: A case-control study was conducted on 208 PE women and 164...
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