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Article

Role of inherited defects of MYH in the development of sporadic colorectal cancer.

Genes, chromosomes & cancer - 1 May 2004

Kambara Takeshi, Whitehall Vicki L J, Spring Kevin J, Barker Melissa A, Arnold Sven, Wynter Coral V A, Matsubara Nagahide, Tanaka Noriaki, Young Joanne P, Leggett Barbara A, Jass Jeremy R

Abstract excerpt

Biallelic germ-line variants of the 8-hydroxyguanine repair gene MYH have been associated with multiple colorectal adenomas that display somatic G:C-->T:A transversions in APC. However, the effect of single germ-line variants has not been widely studied. To examine the relationship between monoal...

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Source

Identifiers

PMID: 15034862
DOI: 10.1002/gcc.20011

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15034862-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Role of inherited defects of MYH in the development of sporadic colorectal cancer.PMID 15034862Read ↗

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