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Article

Pathological features of colorectal carcinomas in MYH‐associated polyposis

17 Jun 2008

Abstract excerpt

AIMS: MYH is a DNA glycosylase in the base excision repair pathway. Germ-line biallelic mutations in the MYH gene are associated with the development of multiple colorectal adenomas and colorectal carcinoma (CRC). A slightly increased risk of CRC is suggested in monoallelic MYH mutation carriers. The aim was to characterize the histopathological features of carcinomas from biallelics and monoallelics. METHODS AND...

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Identifiers

PMID: 18564191
DOI: 10.1111/j.1365-2559.2008.03071.x

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