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Article

Vitamin B-12, apolipoprotein E genotype, and cognitive performance in community-living older adults: evidence of a gene-micronutrient interaction.

The American journal of clinical nutrition - 1 Apr 2009

Feng Lei, Li Jialiang, Yap Keng-Bee, Kua Ee-Heok, Ng Tze-Pin

Abstract excerpt

BACKGROUND: The relation between vitamin B-12 and cognitive function in older adults is unclear. Limited evidence suggests that the relation is modulated by apolipoprotein E epsilon4. Hence, it is important to further examine this gene-nutrient interaction. OBJECTIVE: The aim was to investigate the role of apolipoprotein E (APOE) epsilon4 as a genetic predisposing factor modulating the effect of vitamin B-12 on...

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Identifiers

PMID: 19244370
DOI: 10.3945/ajcn.2008.26969

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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