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Article

APOE genotype modulates the effect of serum calcium levels on cognitive function in old age.

Neurology - 3 Mar 2009

van Vliet P, Oleksik A M, Mooijaart S P, de Craen A J M, Westendorp R G J

Abstract excerpt

OBJECTIVE: The APOE genotype and serum calcium levels have both been associated with cognitive impairment. Animal studies have shown variation in apoE isoforms to play a critical role in intraneuronal calcium homeostasis, but the contribution of this interaction to cognitive function in man is unknown. Here, we studied whether the APOE genotype modulates the association between serum calcium levels and cognition....

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Identifiers

PMID: 19255409
DOI: 10.1212/01.wnl.0000343852.10018.24

Genes

APOE

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