Article
Six years' experience performing RHD genotyping to confirm D- red blood cell units in Germany for preventing anti-D immunizations.
Transfusion - 1 Mar 2009
Flegel Willy A, von Zabern Inge, Wagner Franz F
Abstract excerpt
BACKGROUND: Red blood cell (RBC) units of D+ donors are falsely labeled D- if regular serologic typing fails to detect low D antigen expression or chimerism. The limitations of serology can be overcome by molecular typing. STUDY DESIGN AND METHODS: In January 2002, we introduced a polymerase chain reaction (PCR)-based assay for RHD as a routine test for first-time donors who typed D- by serologic methods...
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