Article
Identification of RHD alleles with the potential of anti-D immunization among seemingly D- blood donors in Upper Austria.
Transfusion - 1 Apr 2009
Polin Helene, Danzer Martin, Gaszner Waltraud, Broda Doris, St-Louis Maryse, Pröll Johannes, Hofer Katja, Gabriel Christian
Abstract excerpt
BACKGROUND: Aberrant RHD alleles leading to a reduced expression of D antigen on the red blood cell (RBC) surface may be mistyped as D- by serology. To quantify the occurrence of weak D, DEL, and D+/- chimera among apparent D- first-time blood donors, polymerase chain reaction (PCR) screening was implemented as a routine service. STUDY DESIGN AND METHODS: A total of 23,330 pretyped D- samples were tested for RHD...
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