Article
Effective molecular RHD typing strategy for blood donations.
Transfusion - 1 Aug 2007
Polin Helene, Danzer Martin, Hofer Katja, Gassner Waltraud, Gabriel Christian
Abstract excerpt
BACKGROUND: More than 50 weak D alleles and numerous partial D alleles have been described to date that can be identified by molecular methods as polymerase chain reaction (PCR) and DNA sequencing of the RHD gene. A real time-based RHD typing scheme was developed and tested during an 8-month period. STUDY DESIGN AND METHODS: A total of 53,347 blood donors and patients were tested with standardized...
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