Article
RHD allelic identification among D-Brazilian blood donors as a routine test using pools of DNA.
Journal of clinical laboratory analysis - 1 Feb 2012
Mota Mariza, Dezan M, Valgueiro M C, Sakashita A M, Kutner J M, Castilho L
Abstract excerpt
BACKGROUND: RHD alleles leading to a reduced expression of D antigen of the red blood cell (RBC) surface may be erroneously typed as D- by serology and may cause anti-D immunizations when transfused to recipients. METHODS: To determine the occurrence of such alleles among apparent D- blood donors, molecular typing was implemented as a routine test using a pool of DNA. A total of 2,450 pretyped D- samples were...
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