Article
RHD variants in Polish blood donors routinely typed as D-.
Transfusion - 1 Nov 2013
Orzińska Agnieszka, Guz Katarzyna, Polin Helene, Pelc-Kłopotowska Monika, Bednarz Justyna, Gieleżyńska Agata, Sliwa Beata, Kowalewska Małgorzata, Pawłowska Elżbieta, Włodarczyk Bogusława, Malaga Alicja Żmudzin Małgorzata, Krzemienowska Magdalena, Srivastava Kshitij, Michalewska Bogumiła, Gabriel Christian, Flegel Willy A, Brojer Ewa
Abstract excerpt
BACKGROUND: Blood donors exhibiting a weak D or DEL phenotypical expression may be mistyped D- by standard serology hence permitting incompatible transfusion to D- recipients. Molecular methods may overcome these technical limits. Our aim was to estimate the frequency of RHD alleles among the apparently D- Polish donor population and to characterize its molecular background. STUDY DESIGN AND METHODS: Plasma pools...
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