Article
Evaluation of the applicability and effectiveness of a molecular strategy for identifying weak D and DEL phenotype among D- blood donors of mixed origin exhibiting high frequency of RHD*Ψ.
Transfusion - 1 Feb 2018
Dezan Marcia Regina, Guardalini Luis Giovani O, Pessoa Elaine, Ribeiro Ingrid Helena, Oliveira Valeria Brito, Luz Fabio, Novac Denise Rossite, Gallucci António, Bonifácio Silvia, Gomes Francisco, Levi José E, Pereira Alexandre C, Krieger Jose E, Mendrone-Junior Alfredo, Rocha Vanderson, Dinardo Carla Luana
Abstract excerpt
BACKGROUND: Molecular tests designed to detect the presence of active RHD gene among D- donors have been successfully applied in people of European ancestry, but not in admixed populations with a considerable frequency of RHD*Ψ. Our goal was to evaluate the performance of a molecular screening tool for identifying active RHD alleles among Brazilian blood donors classified as D- C+ and/or E+. STUDY DESIGN AND...
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