Article
Identification of a conserved F-box protein 6 interactor essential for endocytosis and cytokinesis in fission yeast.
The Biochemical journal - 13 May 2009
Jourdain Isabelle, Spielewoy Nathalie, Thompson James, Dhut Susheela, Yates John R, Toda Takashi
Abstract excerpt
The F-box domain is a degenerated motif consisting of approximately 40 amino acid residues that specifically bind Skp1, a core component of the SCF (Skp1-Cdc53/Cullin 1-F-box protein) ubiquitin ligase. Recent work, mainly performed in budding yeast, indicates that certain F-box proteins form non-SCF complexes together with Skp1 in the absence of cullins and play various roles in cell cycle and signalling...
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