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Article

Etd1p is a novel protein that links the SIN cascade with cytokinesis.

The EMBO journal - 6 Jul 2005

Daga Rafael R, Lahoz Aurelia, Muñoz Manuel J, Moreno Sergio, Jimenez Juan

Abstract excerpt

In animal cells, cytokinesis occurs by constriction of an actomyosin ring. In fission yeast cells, ring constriction is triggered by the septum initiation network (SIN), an SPB-associated GTPase-regulated kinase cascade that coordinates exit from mitosis with cytokinesis. We have identified a novel protein, Etd1p, required to trigger actomyosin ring constriction in fission yeasts. This protein is localised at the...

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Identifiers

PMID: 15933715
DOI: 10.1038/sj.emboj.7600705
PMCID: PMC1173146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Etd1p is a novel protein that links the SIN cascade with cytokinesis.PMID 15933715Read ↗

Proper timing of cytokinesis is regulated by Schizosaccharomyces pombe Etd1.Semantic proximity Read ↗

Feedback regulation of SIN by Etd1 and Rho1 in fission yeast.Semantic proximity Read ↗

Sid2p, a spindle pole body kinase that regulates the onset of cytokinesis.Semantic proximity Read ↗

S. pombe cdc11p, together with sid4p, provides an anchor for septation initiation network proteins on the spindle pole body.Semantic proximity Read ↗

Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN).Semantic proximity Read ↗

Identification of functional domains within the septation initiation network kinase, Cdc7.Semantic proximity Read ↗

Septins regulate the equatorial dynamics of the separation initiation network kinase Sid2p and glucan synthases to ensure proper cytokinesis.Semantic proximity Read ↗

The nuclear kinase Lsk1p positively regulates the septation initiation network and promotes the successful completion of cytokinesis in response to perturbation of the actomyosin ring in Schizosaccharomyces pombe.Semantic proximity Read ↗

The SIN kinase Sid2 regulates cytoplasmic retention of the S. pombe Cdc14-like phosphatase Clp1.Semantic proximity Read ↗

The nucleolar Net1/Cfi1-related protein Dnt1 antagonizes the septation initiation network in fission yeast.Semantic proximity Read ↗

Nuc2p, a subunit of the anaphase-promoting complex, inhibits septation initiation network following cytokinesis in fission yeast.Semantic proximity Read ↗

The Schizosaccharomyces pombe septation initiation network (SIN) is required for spore formation in meiosis.Semantic proximity Read ↗

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