Article
A new function of Skp1 in the mitotic exit of budding yeast Saccharomyces cerevisiae.
Journal of microbiology (Seoul, Korea) - 1 Dec 2006
Kim Namil, Yoon Hayoung, Lee Eunhwa, Song Kiwon
Abstract excerpt
We previously reported that Skp1, a component of the Skp1-Cullin-F-box protein (SCF) complex essential for the timely degradation of cell cycle proteins by ubiquitination, physically interacts with Bfa1, which is a key negative regulator of the mitotic exit network (MEN) in response to diverse checkpoint-activating stresses in budding yeast. In this study, we initially investigated whether the interaction of Skp1...
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