Article
Follistatin interacts with Noggin in the development of the axial skeleton.
Mechanisms of development - 1 Feb 2014
Stafford David A, Monica Stefanie D, Harland Richard M
Abstract excerpt
When compared to single mutants for Follistatin or Noggin, we find that double mutants display a dramatic further reduction in trunk cartilage formation, particularly in the vertebral bodies and proximal ribs. Consistent with these observations, expression of the early sclerotome markers Pax1 and Uncx is diminished in Noggin;Follistatin compound mutants. In contrast, Sim1 expression expands medially in double...
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