Article
TauT protects against cisplatin-induced acute kidney injury (AKI) established in a TauT transgenic mice model.
Advances in experimental medicine and biology - 1 Jan 2009
Han Xiaobin, Chesney Russell W
Abstract excerpt
Cisplatin is a commonly used chemotherapeutic agent that has a major limitation because of its nephrotoxicity. Taurine is an important osmolyte that has been found to protect against cisplatin-induced apoptosis in renal cells in vitro. To determine whether over-expression of hTauT protects agains...
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