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Article

Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2002

Heller-Stilb Birgit, van Roeyen Claudia, Rascher Kristina, Hartwig Hans-Georg, Huth Andrea, Seeliger Mathias W, Warskulat Ulrich, Häussinger Dieter

Abstract excerpt

Taurine is involved in cell volume homeostasis, antioxidant defense, protein stabilization, and stress responses. High levels of intracellular taurine are maintained by a Na+-dependent taurine transporter (TAUT) in the plasma membrane. In view of the immunomodulatory and cytoprotective effects of taurine, a mouse model with a disrupted gene coding for the taurine transporter (taut-/- mice) was generated. These...

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Identifiers

PMID: 11772953
DOI: 10.1096/fj.01-0691fje

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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