Article
Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment response.
The international journal of neuropsychopharmacology - 1 Feb 2010
Domschke Katharina, Lawford Bruce, Laje Gonzalo, Berger Klaus, Young Ross, Morris Phillip, Deckert Jürgen, Arolt Volker, McMahon Francis J, Baune Bernhard T
Abstract excerpt
The brain-derived neurotrophic factor (BDNF) has been suggested to play a pivotal role in the aetiology of affective disorders. In order to further clarify the impact of BDNF gene variation on major depression as well as antidepressant treatment response, association of three BDNF polymorphisms [rs7103411, Val66Met (rs6265) and rs7124442] with major depression and antidepressant treatment response was...
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