Article
Brain-derived neurotrophic factor gene polymorphisms and mirtazapine responses in Koreans with major depression.
Journal of psychopharmacology (Oxford, England) - 1 Dec 2010
Kang R H, Chang H S, Wong M L, Choi M J, Park J Y, Lee H Y, Jung I K, Joe S H, Kim L, Kim S H, Kim Y K, Han C S, Ham B J, Lee H J, Ko Y H, Lee M S, Lee M S
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) is a candidate molecule for influencing the clinical response to antidepressant treatment. The aims of this study were to determine the relationship between the Val66Met polymorphism in the BDNF gene and the response to mirtazapine in 243 Korean subjects with major depressive disorder (MDD). The reduction in the Hamilton Depression score over the 8-week treatment period...
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