Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The G-712A polymorphism of brain-derived neurotrophic factor is associated with major depression but not schizophrenia.

Neuroscience letters - 1 Feb 2011

Sun R F, Zhu Y S, Kuang W J, Liu Y, Li S B

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is needed to support neuronal survival and differentiation. It also promotes synaptic remodeling and modulates the function of many other neurotransmitters. BDNF is implicated in major depression (MD), and to a lesser extent, in schizophrenia. In the current study, we examined BDNF polymorphisms (G-712A, C270T and Val66Met) in 202 patients with MD and 323 patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to BDNF gene

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Schizophrenia

Source

Identifiers

PMID: 21129438
DOI: 10.1016/j.neulet.2010.11.061

Genes

BDNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The G-712A polymorphism of brain-derived neurotrophic factor is associated with major depression but not schizophrenia.PMID 21129438Read ↗

The 712A/G polymorphism of Brain-derived neurotrophic factor is associated with Parkinson's disease but not Major Depressive Disorder in a Chinese Han population.Semantic proximity Read ↗

Brain-derived neurotrophic factor and mental disorders.Semantic proximity Read ↗

No association of genetic variants in BDNF with major depression: a meta- and gene-based analysis.Semantic proximity Read ↗

The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression.Semantic proximity Read ↗

Influence of BDNF variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia.Semantic proximity Read ↗

BDNF Val66Met Variant as a Genetic Risk Factor for Major Depressive Disorder in Saudis.Semantic proximity Read ↗

BDNF gene: functional Val66Met polymorphism in mood disorders and schizophrenia.Semantic proximity Read ↗

Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar DisorderSemantic proximity Read ↗

Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression.Semantic proximity Read ↗

Genetic association study of BDNF in depression: finding from two cohort studies and a meta-analysis.Semantic proximity Read ↗

The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans.Semantic proximity Read ↗

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.