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Article

Evaluating variations of genotype calling: a potential source of spurious associations in genome-wide association studies.

Journal of genetics - 1 Apr 2010

Hong Huixiao, Su Zhenqiang, Ge Weigong, Shi Leming, Perkins Roger, Fang Hong, Mendrick Donna, Tong Weida

Abstract excerpt

Genome-wide association studies (GWAS) examine the entire human genome with the goal of identifying genetic variants (usually single nucleotide polymorphisms (SNPs)) that are associated with phenotypic traits such as disease status and drug response. The discordance of significantly associated SNPs for the same disease identified from different GWAS indicates that false associations exist in such results. In...

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PMID: 20505247
DOI: 10.1007/s12041-010-0011-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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