Article
Runx3-deficient mouse strains circa 2008: resemblance and dissimilarity.
Blood cells, molecules & diseases - 1 Jan 2000
Levanon Ditsa, Groner Yoram
Abstract excerpt
Runx3 is one of the three mammalian Runt domain transcription factors comprising the deeply conserved RUNX gene family. While the three proteins recognize the same DNA-motif, the functional overlaps are minor; each Runx has a distinct subset of biological functions. This lack of functional redundancy is the consequence of a tightly regulated spatio/temporal expression of the genes by transcriptional and...
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