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Article

A novel mutant allele of Mta3 in the mouse: genetic analysis of roles in immunity and androgen biology.

G3 (Bethesda, Md.) - 8 Oct 2025

Chrysovergis Kaliopi, Headley Kathryn, Harper Kathryn M, Moy Sheryl S, Grimm Sara A, Jefferson Wendy N, Sifre Maria I, Mahapatra Debabrata, Rodriguez Yesenia, Williams Carmen J, Wade Paul A

Abstract excerpt

The metastasis associated (MTA) proteins, encoded in mammals by 3 highly similar gene paralogs, Mta1, Mta2, and Mta3, are integral components of the nucleosome remodeling deacetylase (NuRD) complex. While biochemical and molecular studies have probed the functions of the Mta gene family, genetic data in animals is less complete. Here we report the creation of a novel allele of Mta3 in which the first 2 coding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40758820
DOI: 10.1093/g3journal/jkaf171
PMCID: PMC12506663

Genes

MTA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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