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Article

MDM2 SNP309T>G polymorphism and risk of hepatocellular carcinoma: a case-control analysis in a Moroccan population.

Cancer detection and prevention - 1 Jan 2009

Ezzikouri Sayeh, El Feydi Abdellah Essaid, Afifi Rajae, El Kihal Latifa, Benazzouz Mustapha, Hassar Mohammed, Marchio Agnès, Pineau Pascal, Benjelloun Soumaya

Abstract excerpt

BACKGROUND: The Murine double minute 2 (MDM2) gene encodes a negative regulator of the p53 tumor suppressor protein. A single nucleotide polymorphism (SNP) in the MDM2 promoter (a T to G exchange at nucleotide 309) has been reported to produce accelerated tumor formation. The aim of this study was to investigate whether this functional SNP is associated with an enhanced risk of liver tumorigenesis in Moroccan...

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Identifiers

PMID: 19233569
DOI: 10.1016/j.cdp.2009.01.003

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MDM2 SNP309T>G polymorphism and risk of hepatocellular carcinoma: a case-control analysis in a Moroccan population.PMID 19233569Read ↗

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