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Article

MDM2 promoter SNP309 is associated with the risk of hepatocellular carcinoma in patients with chronic hepatitis C.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2006

Dharel Narayan, Kato Naoya, Muroyama Ryosuke, Moriyama Masaru, Shao Run-Xuan, Kawabe Takao, Omata Masao

Abstract excerpt

PURPOSE: A single nucleotide polymorphism (SNP) in the promoter region of MDM2 gene, SNP309, has recently been shown to be associated with accelerated tumor formation in both hereditary and sporadic cancers in humans. However, the association of SNP309 with hepatocellular carcinoma is unknown. We evaluated the association of SNP309 with the risk of hepatocellular carcinoma development among Japanese patients with...

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Share to Aged, 80 and over
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Liver Neoplasms

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins c-mdm2

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Source

Identifiers

PMID: 16914573
DOI: 10.1158/1078-0432.CCR-06-0111

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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