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Article

Serotonin 7 Receptor Variants Are Not Associated with Response to Second-Generation Antipsychotics in Japanese Schizophrenia Patients.

Neuropsychobiology - 1 Jan 2015

Takekita Yoshiteru, Fabbri Chiara, Kato Masaki, Nonen Shinpei, Sakai Shiho, Sunada Naotaka, Koshikawa Yosuke, Wakeno Masataka, Okugawa Gaku, Kinoshita Toshihiko, Serretti Alessandro

Abstract excerpt

BACKGROUND: Individual differences in serotonin 7 receptor (5-HT7R) may result in variable response to antipsychotics with 5-HT7R antagonism. This study investigated the relationship between single nucleotide polymorphisms (SNPs) in the 5-HT7R gene (HTR7) and the efficacy of second-generation antipsychotic drugs with a high affinity for this receptor in Japanese schizophrenia. METHODS: Perospirone or aripiprazole...

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Source

Identifiers

PMID: 26609891
DOI: 10.1159/000441629

Genes

HTR7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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