Article
Family-based genetic association study of insulin-like growth factor I microsatellite markers and premenopausal breast cancer risk.
Breast cancer research and treatment - 1 Nov 2009
Fehringer Gordon, Boyd Norman F, Knight Julia A, Paterson Andrew D, Dite Gillian S, Giles Graham G, Southey Melissa C, Andrulis Irene L, Hopper John L, Ozcelik Hilmi
Abstract excerpt
Several studies suggest that higher circulating insulin-like growth factor I (IGF-I) levels are associated with premenopausal breast cancer risk. Breast cancer risk and circulating IGF-I concentration appear to be partly heritable, thus genetic variation at IGF1 could influence IGF-I levels and breast cancer risk. We investigated the association of IGF1 CA repeat variants with premenopausal breast cancer risk...
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