Article
Distinct SOX9 levels differentially mark stem/progenitor populations and enteroendocrine cells of the small intestine epithelium.
American journal of physiology. Gastrointestinal and liver physiology - 1 May 2009
Formeister Eric J, Sionas Ayn L, Lorance David K, Barkley Carey L, Lee Ginny H, Magness Scott T
Abstract excerpt
SOX transcription factors have the capacity to modulate stem/progenitor cell proliferation and differentiation in a dose-dependent manner. SOX9 is expressed in the small intestine epithelial stem cell zone. Therefore, we hypothesized that differential levels of SOX9 may exist, influencing proliferation and/or differentiation of the small intestine epithelium. Sox9 expression levels in the small intestine were...
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