Article
Modification of the association between serotonin transporter genotype and risk of posttraumatic stress disorder in adults by county-level social environment.
American journal of epidemiology - 15 Mar 2009
Koenen Karestan C, Aiello Allison E, Bakshis Erin, Amstadter Ananda B, Ruggiero Kenneth J, Acierno Ron, Kilpatrick Dean G, Gelernter Joel, Galea Sandro
Abstract excerpt
Although both genetic factors and features of the social environment are important predictors of posttraumatic stress disorder (PTSD), there are few data examining gene-social environment interactions in studies of PTSD. The authors examined whether features of the social environment (county-level crime rate and unemployment) modified the association between the serotonin protein gene (SLC6A4) promoter variant...
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