Article
The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults.
The American journal of psychiatry - 1 Nov 2007
Kilpatrick Dean G, Koenen Karestan C, Ruggiero Kenneth J, Acierno Ron, Galea Sandro, Resnick Heidi S, Roitzsch John, Boyle John, Gelernter Joel
Abstract excerpt
OBJECTIVE: Disasters are associated with increased risk of posttraumatic stress disorder (PTSD) and major depression, but no study, to the authors' knowledge, has determined whether genotype interacts with disaster exposure and social support to moderate risk of these phenotypes. The authors tested the hypothesis that a polymorphism in the serotonin transporter gene (locus, SLC6A4; variant, serotonin 5-HTTLPR)...
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