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Article

Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits.

The American journal of psychiatry - 1 May 2010

Caspi Avshalom, Hariri Ahmad R, Holmes Andrew, Uher Rudolf, Moffitt Terrie E

Abstract excerpt

Evidence of marked variability in response among people exposed to the same environmental risk implies that individual differences in genetic susceptibility might be at work. The study of such Gene-by-Environment (GxE) interactions has gained momentum. In this article, the authors review research about one of the most extensive areas of inquiry: variation in the promoter region of the serotonin transporter gene...

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Identifiers

PMID: 20231323
DOI: 10.1176/appi.ajp.2010.09101452
PMCID: PMC2943341

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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